Misamis Oriental is a province in Northern Mindanao, notable as the location of Cagayan de Oro City — the commercial hub and regional center of Northern Mindanao and a major urban center in Mindanao overall. Cagayan de Oro is the provincial capital, but as a highly urbanized city it is governed independently of the province. The province wraps around CDO, extending eastward along the Macajalar Bay coast and inland into the mountains bordering Bukidnon.
The Cagayan de Oro River flows through the provincial landscape and the city before emptying into Macajalar Bay. This river — known locally as the CDO River — is the source of the province's most recognized tourism activity: white water rafting. The river's upper course through the mountains and foothills provides rapids ranging from Class II to Class IV, accessible within day-trip distance of the city.
Cagayan de Oro has built a reputation as the 'adventure capital of Mindanao' on the strength of its white water rafting industry. The CDO River rafting scene developed in the 1990s and is now one of the most accessible adventure tourism activities in the Philippines, drawing visitors from across the country and abroad.
Beyond the city and the river, Misamis Oriental is an agricultural province. Its inland municipalities produce corn, rice, pineapple, and rubber. Del Monte Philippines, which exports pineapples across the Asia-Pacific, has a processing plant in Cagayan de Oro.
The 2024 census counted 1,729,682 people in Misamis Oriental including Cagayan de Oro, which has more than 700,000 of them. The province has 23 municipalities and two component cities, Gingoog and El Salvador. Its coast is dominated by two bays, Macajalar Bay and Gingoog Bay. Most residents descend from Visayan settlers from Cebu, Bohol, Negros Oriental, Siquijor and Camiguin, while the Higaonon, Binukid and Manobo are the native peoples of the uplands.





