Isabela is the largest province in Luzon and the second largest in the Philippines, covering a vast stretch of the Cagayan Valley — a lowland corridor flanked by the Cordillera to the west and the Sierra Madre to the east. It is primarily an agricultural province, and in 2012 it was the country's top corn producer, with 1,209,524 metric tons, and its second-largest rice producer.
Ilagan City sits in the middle of the Cagayan Valley, on the Cagayan River — the longest river in the Philippines. The city serves as the administrative hub for a province spread across more than 10,000 square kilometers of valley floor, river systems, and forested margins.
Isabela consistently ranks among the top rice and corn-producing provinces in the Philippines. Its broad alluvial valley, well-watered by the Cagayan River system, supports two to three rice crops per year. The province supplies a significant portion of the rice consumed in Metro Manila and the northern Philippines.
The Sierra Madre mountain range, which forms the eastern boundary of Isabela, contains one of the largest remaining tracts of old-growth tropical rainforest in Southeast Asia. The Cagayan Valley and the Sierra Madre represent two completely different landscapes within the same province — the intensive agriculture of the valley floor and the relatively intact wilderness of the eastern mountains.
The 2024 census counted 1,733,048 people in Isabela, including the independent component city of Santiago (150,313), which the census counts with the province. Isabela has 34 municipalities and three cities, Ilagan, the capital and largest local government unit, Cauayan and Santiago, on 12,415 square kilometers, the second-largest provincial area in the country after Palawan. It borders Cagayan to the north, Kalinga, Mountain Province, Ifugao and Nueva Vizcaya to the west, Quirino and Aurora to the south and the Philippine Sea to the east. It is called the Queen Province of the North, and in 2012 it was the country's top corn producer and its second-largest rice producer.







